Hexamethylenediamine — properties & hazards overview

Name: Hexamethylenediamine (HMDA) Formula: C₆H₁₆N₂ CAS: 124-09-4 UN: 2280 (corrosive liquid)
WARNING — Corrosive amine vapour with strong ammoniacal odour. Reacts with acids and oxidizers. Causes severe burns to skin and eyes; vapours irritate the respiratory tract.
Boiling point
≈ 204 °C
Melting point
≈ 42 °C
Vapour pressure (20 °C)
< 0.1 hPa (low)
Water solubility
Miscible
Flammability
Combustible liquid
Toxicity
Corrosive vapour
Chronic risk
Sensitization possible
Environmental
Toxic to aquatic life
PropertyValue / Note
Physical state Colourless to pale-yellow hygroscopic liquid or low-melting solid with strong ammonia/amine odour.
Density (20 °C) ≈ 0.88 g/cm³
Odour threshold Low (detectable at a few ppm); intense irritant at higher concentrations.
Reactivity Strong base; reacts with acids to form salts, with oxidants to give exothermic reactions; attacks copper and zinc.
Typical sources Polyamide (nylon-6,6) manufacturing, epoxy curing agents, polyurethane additives, amine neutralization or vent gases.
Typical analytical detection FTIR (NH₂ stretching, real-time gas); FID (after oxidation to CO₂); PID (screening if vapour present); NDIR (limited selectivity, high ppm); Amine-specific colorimetric tubes (spot checks); Dust analysis for condensed or neutralized aerosols.

*Indicative data; confirm with SDS and process-specific emission characterization.

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